J Pediatr. 2013 Dec 19;
Authors: van Sorge AJ, Termote JU, Kerkhoff FT, van Rijn LJ, Simonsz HJ, Peer PG, Schalij-Delfos NE
Abstract
OBJECTIVES: To study the incidence and risk factors for retinopathy of prematurity (ROP) in the Netherlands.
STUDY DESIGN: Prospective, approximating population-based study that included infants with gestational age (GA) 7 days (OR 1.6, 95% CI 1.1-2.5, P = .02). Prenatal glucocorticoids (OR 0.6, 95% CI 0.4-0.8, P < .001) and female sex (OR 0.7, 95% CI 0.5-0.99, P = .04) showed a lesser incidence of ROP. iNO remained significant after correction for all significant factors (OR 2.6, 95% CI 1.1-6.2, P = .03).
CONCLUSION: In addition to established risk factors (GA, BW, stay at a neonatal intensive care unit >28 days, and artificial ventilation >7 days), treatment with iNO as risk factor for ROP is a novel finding.
PMID: 24360994 [PubMed - as supplied by publisher]
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